The Challenges of Polydisperse SAXS Data Analysis: Two SAXS Studies of PICK1 Produce Different Structural Models
نویسندگان
چکیده
منابع مشابه
Response to The Challenges of Polydisperse SAXS Data Analysis: Two Different SAXS Studies of PICK1 Produce Different Structural Models.
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Computational Analysis of SAXS Data Acquisition
Small-angle x-ray scattering (SAXS) is an experimental biophysical method used for gaining insight into the structure of large biomolecular complexes. Under appropriate chemical conditions, the information obtained from a SAXS experiment can be equated to the pair distribution function, which is the distribution of distances between every pair of points in the complex. Here we develop a mathema...
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The exosome is a large protein complex conserved in all eukaryotes that possesses 3’-5’ exoribonuclease activity [1]. It is playing a major role in RNA turnover and surveillance as well as processing of stable RNA species [2,3,1,4,5]. The exosome is composed of six distinct subunits homologous to the catalytic domains of ring shaped phosphorolytic bacterial RNase PH and PNPase (Rrp41, Rrp42, Rr...
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ژورنال
عنوان ژورنال: Structure
سال: 2015
ISSN: 0969-2126
DOI: 10.1016/j.str.2015.10.007